Trans-generational effects of prenatal stress in quail.

Trans-generational effects of prenatal stress on the neuroendocrine stress axis in rats.

A temperature shock can lead to trans-generational immune priming in the Red Flour Beetle, Tribolium castaneum

Trans-generational immune priming (TGIP) describes the transfer of immune stimulation to the next generation. As stress and immunity are closely connected, we here address the question whether trans-generational effects on immunity and resistance can also be elicited by a nonpathogen stress treatment of parents. General stressors have been shown to induce immunity to pathogens within individual...

Cross-generational effect of prenatal morphine exposure on neurobehavioral development of rat pups.

Prenatal exposure to opiates can have devastating effects on the development of human fetuses and may induce long-term physical and neurobehavioral changes during postnatal maturation. The present study was aimed at identifying cross-generational effects of prenatal morphine exposure in Sprague-Dawley rats. Pregnant rats were injected subcutaneously with either saline or morphine (10 mg/kg) twi...

Disease Load at Conception Predicts Survival in Later Epidemics in a Historical French-Canadian Cohort, Suggesting Functional Trans-Generational Effects in Humans

OBJECTIVE Functional trans-generational and parental effects are potentially important determinants of health in several mammals. For humans, the existing evidence is weak. We investigate whether disease exposure triggers functional trans-generational response effects among humans by analyzing siblings who were conceived under different disease loads, and comparing their mortality in later epid...

The Effects of Silymarin on Oxidative Status and Bone Characteristics in Japanese Quail Subjected to Oxidative Stress Induced by Carbon Tetrachloride

This experiment was conducted to assess the effects of Silymarin on oxidative status, bone characteristics, and some blood parameters in Japanese quail subjected to oxidative stress induced by carbon tetrachloride (CCl4). The experiment was performed as a completely randomized design with four replicates, each with 30 birds, using a 2 × 2 factorial arrangement with two doses of Silymarin (0 and...